You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

See also:

Cardiovascular: Cardiac status/risk factors (prior to initiation); blood pressure (periodically during treatment in patients with PAH on concomitant anti-hypertensive agents) Drug Interactions: For concomitant use of medications that may be contraindicated or for dose adjustment (at baseline and during treatment) Ocular: NAION risk factors (prior to initiation) Read the US FDA-approved patient labeling (Patient Information and/or Instructions for Use). Tell your healthcare provider about all of the medicines you (or your child take). Regular and/or intermittent use of nitric oxide donors (e.g., organic nitrates or nitrites) in any form Other PDE5 inhibitors or products containing sildenafil Seek immediate medical attention in the event of: Sudden loss of vision in one or both eyes Sudden decrease or loss of hearing; may be accompanied by tinnitus and dizziness An erection that persists longer than 4 hours. It is not recommended to take this drug more than once a day. This medication can cause your blood pressure to unsafely drop suddenly if it is taken with certain other medicines.

Organic Nitrates, Nitrites, and Nitric Oxide Donors

Stop sexual activity and seek medical attention if you experience symptoms such as chest pain, dizziness, or nausea during sex, or if you have any side effect that bothers you or does not go away. Use protective measures to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV). Reference details for licensed healthcare facility review and verification. Unless explicitly stated in writing, no direct affiliation, sponsorship, or endorsement by individual product manufacturers with Premium Rx National, LLC should be implied. All brand names, trade names, and trademarks are the property of their respective owners and are presented solely for accurate product identification and informational reference. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

  • Sildenafil citrate 100 mg should be taken approximately 30-60 minutes before sexual activity.
  • Avoid taking sildenafil with a high-fat meal, as it may delay absorption.
  • Do not exceed one dose in 24 hours to reduce risk of side effects.

Talk to your pharmacist for more details.

  • Female sexual arousal disorder is not treated with sildenafil 100 mg.
  • The medication is intended for adult male patients only.
  • Always obtain sildenafil from reputable pharmacies to avoid counterfeit drugs.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure) penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease) conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma) eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION) This drug may make you dizzy or cause vision problems.

  • Common side effects include headache, flushing, nasal congestion, and dizziness.
  • Serious side effects like vision loss or prolonged erections require immediate medical attention.
  • Always consult a healthcare provider before starting sildenafil 100 mg.

Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely.

Parameter Value Notes
Absorption Time 30-60 minutes Prompt onset after oral ingestion
Peak Plasma Levels 60 minutes Max concentration reached
Bioavailability 40% Due to first-pass metabolism
Metabolic Pathway Liver (CYP3A4) Hepatic metabolism primarily
Excretion Mainly feces, minor urine Elimination half-life approx. 4 hours

Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, sildenafil should be used only when clearly needed.

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Since high blood pressure in the lungs is a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, discuss with your doctor right away the benefits and risks of using this medication during pregnancy.

What should I know about storage and disposal of this medication?

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if your condition does not get better. Dizziness, headache, flushing, or stomach upset may occur. Vision changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur.

Related treatment guides

If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Sexual activity may put extra strain sildenafil generic on your heart, especially if you have heart problems. Drug interactions may change how your medications work or increase your risk for serious side effects.

Condition Recommended Range Additional Tips
Temperature 20-25°C (68-77°F) Keep away from moisture and heat
Humidity Low humidity Store in a dry place
Light Exposure Protect from direct light Store in original container
Shelf Life 2-3 years depending on manufacturer Check expiry date before use

This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

Other Comments

Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Drug Label Information

If you have heart problems and experience any of these serious side effects while having sex, stop and get medical help right away: Rarely, sudden decreased vision, or even permanent blindness, may occur in one or both eyes (NAION). If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke. Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur. Some products that may interact with this drug are: Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide) recreational drugs called "poppers" containing amyl or butyl nitrite If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure.

About this article

Sildenafil Citrate 100 mg / 1 Tablet is tracked under NDC 80425-0503-02 and rolls up into product family 80425-0503. Use this page to review package-level identifiers before comparing related family pages or starting a quote review. Click a tag to refine the catalog view around this product reference. Use official labeling and directory references to confirm presentation details while your team reviews the PRN catalog entry and related sourcing paths. These nearby package-level pages can help healthcare teams compare related packaging or presentation differences inside the same product-NDC family.

Sildenafil vs. tadalafil

Sildenafil Citrate 100 mg / 1 Tablet 60 Tablet, NDC 80425-0503-02, is a Advanced Rx of Tennessee, LLC 100 mg / 1 tablet presentation packaged as 60 Tablet. Possible 10-digit display formats: 80425-503-02 (8042550302), 80425-0503-2 (8042505032) Multiple 10-digit display-format aliases can map to the same stored 11-digit billing NDC, so these are shown as search aliases rather than a single asserted package format. Other package sizes in this family: 30 Tablet, 90 Tablet Compare related presentations: Sildenafil Citrate 100 mg / 1 Tablet 30 Tablet, Sildenafil Citrate 100 mg / 1 Tablet 90 Tablet Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a person get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works.

Pregnancy & Lactation

Using an effective barrier method (latex or polyurethane condom/dental dams) during sexual activity will help to decrease your risk of infection. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Sildenafil is also available in other brands and strengths for high blood pressure in the lungs (pulmonary hypertension). Read the Patient Information Leaflet if available from your pharmacist before you start taking sildenafil and each time you get a refill.

Hypertension pulmonaire

If you have any questions, ask your doctor or pharmacist. To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before works best). This medication may take longer to start working if you take it with a high-fat meal. Do not take more than once daily as needed. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), mifepristone, rifampin, ritonavir, among others.

  • Sildenafil citrate 100 mg is sometimes used off-label for other health conditions.
  • It is important to follow the prescribed dose and schedule advised by your doctor.
  • discontinuing use abruptly is generally safe but consult your doctor if concerns arise.